Chronically exhausted with Parkinson's disease?

01.07.2026 -  

Magdeburg University Medical Center is seeking participants for a clinical trial of a new, non-pharmacological treatment for fatigue.

Magdeburg University Medical Center is seeking people with Parkinson’s disease who suffer from persistent exhaustion (fatigue) for the clinical trial “ReVita”. The research team is investigating whether gentle electrical stimulation of the vagus nerve at the ear (transcutaneous auricular vagus nerve stimulation, taVNS) can alleviate fatigue symptoms and improve quality of life.

Fatigue is one of the most common and highly debilitating symptoms associated with Parkinson’s disease. Many people with the condition report severe physical and mental exhaustion that significantly limits their daily lives. To date, only limited treatment options are available for this condition.

As part of the study, participants will independently apply non-invasive vagus nerve stimulation at home for a period of four weeks following an initial training session. In addition, the research team is investigating how the treatment affects brain activity, heart rate variability, and other biological parameters.

The study is part of the ERDF-funded project “KSMED – Clinical Studies and Trials at the Magdeburg Medical School”, which strengthens patient-centered clinical research and explores new therapeutic approaches for chronic diseases.

Who can participate?

Adults with Parkinson’s disease who experience fatigue or significant exhaustion in their daily lives.

For more information and to register, visit https://redcap.link/revita-info

Scientific Contact

Dr. Maria Kühne and Dr. Anni Richter, Faculty of Medicine at Otto von Guericke University Magdeburg, revita@med.ovgu.de

 

Das Magdeburger Forschungsteam im Projekt REVITA_Sarah Kossmann_UMMD

The Magdeburg research team for the ReVita study (from left): Prof. Dr. Tino Zähle, Head of the Department of Neuropsychology and Director of the Institute of Medical Psychology in Magdeburg, Dr. Anni Richter, and Dr. Maria Kühne, research associates. Photographer: Sarah Kossmann/Magdeburg University Medical Center

tVNS Stimulationsgerät zur Stimulation des Vagusnervs bei Fatigue_Foto Sarah Kossmann_UMMD

A tVNS stimulator is used for non-invasive vagus nerve stimulation at the ear. Photographer: Sarah Kossmann/Magdeburg University Medical Center

Last Modification: 06.07.2026 - Contact Person:

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